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Editor's Choice & Editorials
Background Multidisciplinary cancer conferences consist of regular meetings between diverse specialists working together to share clinical decision making in cancer care. The aim of this study was to systematically review and meta-analyze the effect of multidisciplinary cancer conference intervention on the overall survival of patients with cancer. Methods A systematic literature search was ...
Background The proteome is an important reservoir of potential therapeutic targets for cancer. This study aimed to examine the causal associations between plasma proteins and cancer risk and to identify proteins with cross-cancer effects. Methods Genetic instruments for 3991 plasma proteins were extracted from a large-scale proteomic study. Summary-level data of 13 site-specific cancers were ...
Background Intratumor heterogeneity drives disease progression and treatment resistance, which can lead to poor patient outcomes. Here, we present a computational approach for quantification of cancer cell diversity in routine hematoxylin-eosin–stained histopathology images. Methods We analyzed publicly available digitized whole-slide hematoxylin-eosin images for 2000 patients. Four tumor types ...
Background The impact of ongoing efforts to decrease opioid use on patients with cancer remains undefined. Our objective was to determine trends in new and additional opioid use in patients with and without cancer. Methods This retrospective cohort study used data from Surveillance, Epidemiology, and End Results program–Medicare for opioid-naive patients with solid tumor malignancies diagnosed ...
Background Human papillomavirus (HPV) vaccination has shown high efficacy against anal HPV infection and lesions in clinical trials, and the HPV prevalence and type distribution in anal precancers and cancer predict a high preventable potential for HPV vaccination. However, the real-world effectiveness of HPV vaccination against anal high-grade lesions and cancer is yet to be shown. Methods We ...
Opioids and Cancer Collection
Explore a selection of articles from JNCI and JNCI Cancer Spectrum on opioid use in cancer patients and survivors.
Diversity, Equity, and Inclusion Collection
As a part of their Diversity, Equity, and Inclusion initiative, JNCI and JNCI Cancer Spectrum have curated a collection of articles that foreground diversity, equity, and inclusion in their research.
COVID-19 Collection
JNCI and JNCI Cancer Spectrum have published a number of peer-reviewed, cancer-relevant manuscripts related to the pandemic. Explore the freely available articles in this collection.
Diversity, Equity, and Inclusion for the JNCI Journals
In 2022, the JNCI journals launched a DEI initiative, committing to increase diversity and inclusion of underrepresented groups in the peer review process and research dissemination. 1 year on, the teams provide an update. Read the editorial here.
JNCI Cancer Spectrum
JNCI Cancer Spectrum is a peer-reviewed, open-access journal. It publishes manuscripts that describe new findings of particular significance across a full range of clinical and translational cancer research, including prevention, screening, and treatment, as well as clinically relevant epidemiologic, public health, and policy research.
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